Mount Sinai surgeon James Gladstone, MD, performed the nation’s first implantation of Biocart II

Cartilage cell transplantation, known as Autologous Cell Implantation (ACI), is a new technology used to replace damaged cartilage in the knee joint. The first implantation of Biocart II, a novel second generation cartilage cell transplantation system, was performed on February 18, 2009 by Dr. James Gladstone at The Mount Sinai Medical Center, as part of an FDA approved Phase II clinical trial. This was the first “second generation cartilage cell transplantation” performed in the United States.

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